Search results for "18f fdg pet"
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Factor analysis-based approach for early uptake automatic quantification of breast cancer by 18F-FDG PET images sequence
2014
International audience; Factor Analysis of Medical Image Sequences (FAMIS) is recognized as one pioneer successfully used approach for analyzing especially dynamic images' sequence for estimating kinetics and associated compartments having a physiological meaning. Some studies tried to extend the exploring of this approach to analyze Positron Emission Tomography (PET) image modality for dynamic sequences. PET images with 18F-fluorodesoxyglucose (18F-FDG) is the gold standard for in vivo, evaluation of tumor glucose metabolism and is widely used in clinical oncology. In this paper, a novel approach is proposed to obtain an automated quantification method for early accumulation of 18F-FDG tra…
[18F]FDG-PET predicts complete pathological response of breast cancer to neoadjuvant chemotherapy
2007
To evaluate, in breast cancer patients treated by neoadjuvant chemotherapy, the predictive value of reduction in FDG uptake with regard to complete pathological response (pCR).Forty-seven women with non-metastatic, non-inflammatory, large or locally advanced breast cancer were included. Tumour uptake of FDG was evaluated before and after the first course of neoadjuvant chemotherapy. Four indices were used: maximal and average SUV without or with correction by body surface area and glycaemia (SUV(max), SUV(avg), SUV(max-BSA-G) and SUV(avg-BSA-G), respectively). The predictive value of reduction in FDG uptake with respect to pCR was studied by logistic regression analysis. Relationships betwe…
Development of a gene panel for 18F-FDG PET positivity prediction in gastric cancer.
2020
420 Background: 18F-FDG PET is widely used in clinical cancer diagnostics. However, 18F-FDG PET scan in gastric cancer (GC) is still controversial because of its lower sensitivity in diagnosis and staging compared to other imaging modalities. The purpose of this study was to establish a gene panel for 18F-FDG PET positivity in GC by using patient-derived xenografts (PDXs). Methods: BALB/c nude mice were subcutaneously implanted with 30 cases of GC PDX tissues and underwent a simultaneous PET/MRI scanner. Using RNA-seq data of the 30 GC PDXs for training set, we constructed a gene co-expression network which was correlated with the maximal standardized uptake values (SUVmax). The least abso…